Co-Expression of TIGIT and Helios Marks Immunosenescent CD8+ T Cells During Aging
Aging leads to alterations in the immune system that result in ineffective responsiveness against pathogens.Features of this process, collectively known as immunosenescence, accumulate in CD8+ T cells with age and have been ascribed to differentiation of these cells during the course of life.Here we aimed to identify novel markers in CD8+ T cells a